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Science
Grayanotoxin, batch variability, and what the studies actually establish.
2 articles.
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Grayanotoxin Explained
Grayanotoxins are a family of related plant compounds, not a single chemical, and their action is on voltage-gated sodium channels in nerve and muscle cells.
We publish no dosing figures
You will not find a spoon count, a weight, a volume or a "start with this much" anywhere on this site, and that is a deliberate editorial rule rather than an oversight.
Grayanotoxin content varies between batches by more than an order of magnitude, so any figure we printed would be wrong for most jars and dangerous for some. A figure that is wrong in the direction of "more" is the exact failure mode that fills the case reports.
There is no established safe amount. Published poisoning cases involve small quantities, and the only people who should be advising you about your own body are clinicians who can see your history.
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