Grayanotoxins are a family of related plant compounds, not a single chemical, and their action is on voltage-gated sodium channels in nerve and muscle cells.
By eoin@realmadhoney.com
Published 21 August 2026. Last checked 21 August 2026.
What this page covers
This is a stub. The body is written against sources before publication; the structural fields below already drive the article furniture.
What the evidence supports
Where the evidence is thin we say so in the sentence rather than in a footnote.
Why this page publishes no dose
We publish no dosing figures
You will not find a spoon count, a weight, a volume or a "start with this much" anywhere on this site, and that is a deliberate editorial rule rather than an oversight.
Grayanotoxin content varies between batches by more than an order of magnitude, so any figure we printed would be wrong for most jars and dangerous for some. A figure that is wrong in the direction of "more" is the exact failure mode that fills the case reports.
There is no established safe amount. Published poisoning cases involve small quantities, and the only people who should be advising you about your own body are clinicians who can see your history.
A reader-supported information site. We publish articles only: nothing here is for sale, nobody pays for coverage, and we link to no traders. General information only, not medical or legal advice, and no substitute for a clinician or a poisons centre.
Follow Us On
Share this
One email a month, when there is something worth saying.
New articles, changes to any of the legal-status pages, and a short note on any study worth reading. If a month passes with nothing substantial, you get nothing: we would rather skip than pad. No sponsors, no seller mentions, no third-party sharing.